The story of Fullmetal Alchemist: Brotherhood follows the adventures of the Elric brothers, two young alchemists cursed after an ill-fated attempt to bring their mother back from the dead during which Edward suffered the horrifying loss of a leg and arm while Alphonse's soul was ensnared in a medieval suit of armour. Driven by their strong relationship and remarkable skills they begin a new, battle-packed adventure on the trail of the philosopher's stone. Only the stone has the power to restore their bodies. This time they're fighting for more than just their lives.
In Fullmetal Alchemist: Brotherhood the fights go down in a series of different battle arenas where players can flex their spectacular alchemist abilities, use the terrain's topography strategically to gain the upper hand, and judiciously launch special Combination Attacks with their battle partner to turn the tide of battle. The Multiplayer Mode lets between two and four players co-operate or fight against each other via ad hoc wi-fi to find out once and for all who has the most powerful alchemy of all at their fingertips.
Historien følger eventyrene til Elric-brødrene, to unge alkymister som det er blitt lyst en forbannelse over etter at de prøvde å hente moren tilbake fra dødsriket I ulykken mistet Edward beinet og en av armene, og brorens sjel er blitt overført til en middelalderrustning. Nå ser de etter de vises sten for å få tilbake kroppene sine, finne den savnede faren og gjenopplive moren.